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ea0037gp.02.04 | Adrenal (1) | ECE2015

Mortality in patients with incidentally discovered adrenal adenomas: the experience of San Luigi Hospital

Reimondo Giuseppe , Coletta Marcella , Peraga Giulia , Pia Anna , Pellegrino Micaela , Massaglia Chiara , Zaggia Barbara , Cosio Paolo , Mbachu Elena , Borretta Giorgio , Terzolo Massimo

Background: Adrenal incidentalomas are found in 37% of radiological series and many of them are adrenal adenomas. Autonomous cortisol secretion without clinical signs of overt hypercortisolism is a common finding in these patients. Studies reported metabolic derangement and increased cardiovascular risk associated with this state of subtle cortisol excess, however scanty data are available on the natural history of this condition.Aim: To assess the...

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ea0056p14 | Adrenal cortex (to include Cushing's) | ECE2018

Preoperative treatment with metyrapone in patient with Cushing’s syndrome due to adrenal adenoma: a pilot prospective study

Puglisi Soraya , Perotti Paola , Barbot Mattia , Cosio Paolo , Scaroni Carla , Stigliano Antonio , Lardo Pina , Morelli Valentina , Polledri Elisa , Chiodini Iacopo , Reimondo Giuseppe , Pia Anna , Terzolo Massimo

Background and objectives: Metyrapone has been approved for the treatment of patients with Cushings syndrome from all causes, but only few retrospective clinical studies are available. The aim of our study was the prospective assessment of metyrapone as pre-operative treatment.Methods: Before adrenalectomy, 7 patients with ACTH-independent Cushings syndrome due to adrenal adenoma were prospectively treated with metyrapone for 3 months, with e...

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Endocrine Abstracts

Mortality in patients with incidentally discovered adrenal adenomas: the experience of San Luigi Hospital

Preoperative treatment with metyrapone in patient with Cushing’s syndrome due to adrenal adenoma: a pilot prospective study

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